Arthrosamid®
Arthrosamid® is a new type of treatment for knee osteoarthritis. In suitable patients, it can be an effective alternative to other treatments like steroid injections or potentially knee replacement surgery. Based on an innovative non-biodegradable hydrogel technology, Arthrosamid® is 97.5% water with 2.5% being a cross linked polyacrylamide backbone. When injected into the knee, Arthrosamid® binds to the joint lining, which is often a driver of pain in arthritis. It has been reported in the DAISY study to provide sustained pain relief without the need for repeated injections.
Arthrosamid® is an intra-articular polyacrylamide hydrogel injection (iPAAG) for the symptomatic treatment of knee osteoarthritis. Once injected into your knee joint cavity, Arthrosamid® has been shown to integrate into the synovium (lining of your inner joint capsule) creating a cushion-like effect and inhibiting the inflammation pathways that can cause knee pain.
Arthrosamid® is a simple out-patient procedure that means you can go home the same day.
It is safe for intended use and is biocompatible which allows it to integrate with the knee's joint lining. The overall safety profile of the hydrogel has undergone over two decades of research and development with approximately 1,000,000 hydrogel units used for various indications in the body.
In clinical trials, patients reported a reduction in their pain levels by Week 4 after their injection. The reduction in pain was sustained at 3 years. Arthrosamid® trials continue to follow patients for 5 years.
Clinical trials reported no serious side effects following treatment with Arthrosamid®. The most commonly reported side effects were joint discomfort and a sensation of joint swelling, which were mostly mild in severity and lasting a few days to weeks.
The overall safety profile of the injectable hydrogel has been established over the last 20 years with its use for various indications in the body.
When will the treatment start to work?
Patients can see the benefits around 4 weeks after treatment. However, effects may take 3-4 months to be fully felt
Is Arthrosamid® safe?
Arthrosamid® is safe for intended use and is biocompatible which allows it to integrate with the tissues in your knee. The overall safety profile of the hydrogel has undergone over two decades of research and development with approximately 1,000,000 hydrogel units used for various indications in the body.
Will I be able to be active as usual after my treatment?
It is recommended that you reduce your activity level for the first 2 days after treatment. Then for about 2 weeks after you should limit to normal activities of daily living.
How long can I expect the benefits to last?
In a prospective study comparing Arthrosamid® to Hyaluronic Acid the reduction in pain has been shown to last 3 years.
Who can be treated with Arthrosamid®?
Based on studies to date, patients who are less that 65 years old with mild or moderate arthritis in their knee are likely to have the best response to treatment. It can still be effective in older patients and those with more severe arthritis, but results become less predicable with increasing age and severity. A consultation is needed before considering this injection, in order to evaluate clinical presentation and knee imaging.
How is an Arthrosamid® injection performed?
Arthrosamid® Enquiry form
